FAQs
common Questions
Explore Common Questions About Amarbio
About nanomake-L
How is nanomake-L different from existing microfluidic systems on the market?
nanomake-L is an advanced automated microfluidic platform designed for versatility and efficiency. It features multi-use microfluidic chips, supports a wide range of flow rates, and includes three configurable precursor pumps, in-line dilution, and a built-in washing program. These capabilities ensure system reusability for multiple runs, making it a highly adaptable and user-friendly solution.
What types of formulations can be prepared?
nanomake-L is a versatile platform capable of preparing a wide range of formulations, including lipid nanoparticles (LNPs), polymeric nanoparticles, emulsions, liposomes, microspheres, and other self-assembled nanostructures
What is the particle size range that can be achieved with nanomake-L?
nanomake-L allows precise optimization of particle sizes directly on the microfluidic chip, covering a wide range from nanometres to microns. Typical size ranges include 50–100 nm for LNPs, 80–200 nm for polymeric nanoparticles, and 50–100 µm for microspheres, depending on formulation parameters and flow conditions.
How reproducible are the results between runs?
The system ensures high reproducibility due to precise flow control, stable mixing conditions, and automation. Users typically observe <5% variability in particle size between replicate runs under identical settings.
Can nanomake-L handle multiple formulations in a single session?
Yes, its automated wash cycle and multi-use chips enable seamless transition between formulations with minimal cross-contamination risk.
System Capabilities and Hardware
What is the range of flow rates for nanomake-L?
nanomake-L supports a range of flow rates from to 100 µL/min to 50 mL/min.
What is the sample collection volume range for nanomake-L?
nanomake-L supports a collection volume range from to 0.1 mL to 10 mL depending on the syringe configuration.
What is the lowest volume required for process optimization?
The system requires minimum of 0.5 mL of sample collection volume for efficient process optimization.
What is the material of the microfluidic chip?
The microfluidic chip is available in different materials (e.g., Teflon, cyclic-olefin copolymer) based on the material compatibility with the fluid system.
What are the available syringe sizes for nanomake-L?
nanomake-L comes with a set of 500 µL, 1, 2.5, 5, 10 mL glass syringes.
Operation, Maintenance and Compliance
Does nanomake-L support 21 CFR Part 11 compliance?
Yes, nanomake-L offers optional 21 CFR Part 11 compliance for electronic records and signatures.
How do you address microchannel clogging issues?
We employ advanced design and operational strategies to minimize clogging and ensure uninterrupted flow. Detailed protocols to prevent microchannel clogging is provided in the user manual.
How do you clean the system?
The system is compatible with a wide range of commonly used cleaning solvents, including isopropyl alcohol, ethanol, acetone, and nuclease-free water. Cleaning procedures may vary depending on the materials and formulations used and should be performed using solvents compatible with your application and device components. A detailed, step-by-step cleaning protocol is provided in the user manual.
What happens if a part needs replacement?
We provide spare parts and offer technical support for quick turnaround. Most user-replaceable components can be swapped easily on-site.
Support and Services
Is design customization available for nanomake-L?
Yes, we can customize the system's design to meet your specific needs. Contact us at info@amarbiosystems.com to discuss your requirements.
Can I request a demo for nanomake-L?
Yes, we offer demonstrations of nanomake-L. Please reach out to us at info@amarbiosystems.com to schedule a session.
Do you provide training for new users?
Yes, we offer comprehensive training (virtual or on-site) covering system operation, cleaning, and formulation optimization
Are there ready-to-use protocols available?
Yes, we provide standard protocols for common LNP and nanoparticle formulations, which can be further customized based on your project needs.
Do you provide remote or on-site support?
Yes, we offer both remote troubleshooting and on-site technical support based on your location and service agreement.
Unlock Insights Through A Free Expert Session
Dictum phasellus vehicula nulla sed mus parturient. Himenaeos porta sapien felis parturient urna.
Need more help?
Have Complex Questions? Let’s Explore Them Together
Customer Support
Aliquam ullamcorper hendrerit nullam imperdiet et scelerisque gravida fames vivamus facilisis eleifend
Ticket Support
Aliquam ullamcorper hendrerit nullam imperdiet et scelerisque gravida fames vivamus facilisis eleifend
Free Insight
Aliquam ullamcorper hendrerit nullam imperdiet et scelerisque gravida fames vivamus facilisis eleifend